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PROBLEMS
WITH DIAGNOSIS AND MANAGEMENT OF HYPOTHYROIDISM
INTRODUCTION
THE
TESTING OF BLOOD FOR THYROID FUNCTION GENERATES DATA
WHICH IS THEN INTERPRETED. THE UPPER AND LOWER LIMITS OF THIS DATA
ARE OPEN TO MISINTERPRETATION.
WHO DECIDED THAT THE PARAMETERS SET FOR BLOOD TEST RESULTS OF THYROID
FUNCTION WERE TO BE THE SOLE INDICTACTOR FOR DIAGNOSIS?
Hypothyroidism
(under active thyroid gland) can go undetected for many years, because
unfortunately most of the medical profession are relying totally on
the reference ranges set for the blood test results of
thyroid conditions INSTEAD
OF USING THEM AS AN INDICATOR ONLY.
This problem is world wide!
Sir Richard Bayliss a Trustee of the British Thyroid Foundation UK
states, "The reference values are made up of 95% fiducial limits
of so-called healthy people".
Now lets break this down into language we can understand. It
is, an assumed fixed basis of comparison of so-called healthy
people. The words assumed and so-called
are very loose. Therefore if the starting point of the reference values
is flexible so the interpretation of the blood test result must be
also be flexible. This is not happening. There is too much rigidity
upon interpretation!
The blood test for measuring the levels of thyroid stimulating hormone(TSH)
is said to be the most sensitive test and is the most commonly used
blood test for measuring thyroid hormones. Does it tell us how much
of the hormones are usable? REF: Hypothyroidism: The Unsuspected Illness
by Dr Broda O Barnes and Lawrence Galton ISBN 0-690-01029-X - Publisher
- Harper & Row Publishers, New York.
Thyroid stimulating hormone (TSH) produced from the pituitary prompts
the thyroid gland to produce hormones. When the TSH is raised above
the reference interval the patient is diagnosed with either sub-clinical
hypothyroidism (symptoms usually absent) or overt hypothyroidism
(symptoms usually present). According to Weetman: Definition of
hypothyroidism BMJ Symptoms are not considered a criterion for
sub-clinical hypothyroidism by some authorities!
INTERESTING!
BLOOD
TESTS THAT ARE USUALLY CARRIED OUT FOR THYROID FUNCTION TO ASCERTAIN
THE LEVELS OF HORMONE IN THE BLOOD ARE SET OUT BELOW: -
TSH = THYROID
STIMULATING HORMONE
FT4 = ACTUAL
HORMONE
FT3 =
ACTUAL HORMONE = MORE ACTIVE HORMONE
When a TSH blood test is carried out and the result is returned normal
the biochemist at the laboratory decides there is no need to carry
out a T4 or T3 blood test even if it has been specifically requested
by the doctor. The patient is told you do not have a thyroid condition,
and that, for the patient, is the end of the matter. If the patient
is still presenting with signs and symptoms it would seem prudent
at this juncture to investigate further.
1 TSH levels are normal in approximately 50% of patients with hypothyroidism
secondary to hypothalamic or pituitary disease.REF: Secondary thyroid
disorders - Medicine International 1993 The Medicine Group (Journals)
Ltd.
2 The patient may not be converting from T4 hormone to T3 hormone.
REF: Dr John Lowes book, titled METABOLIC TREATMENT FOR FIBROMYALGIA
page 277.
3 There may be low adrenal reserve.
4 The patient may have antibodies to the thyroid tissue.
5 Thyroid hormone resistance syndrome.
6 Fluorides imitate TSH and so many of the blood test results are
incorrect in their value.
NO
CONSENSUS OF OPINION WITHIN THE MEDICAL PROFESSION
IN
DIAGNOSING AND MANAGING HYPOTHYROIDISM
A patient, presenting with signs and symptoms of hypothyroidism with
an FT4 of 0.1 above the lower limit will be told you are in the normal
range. And a patient, with the same signs and symptoms who has
an FT4 0.1 below the lower limit will be diagnosed with hypothyroidism
and treated. Some presenting with signs and symptoms with TSH levels
above the upper limit are told they are "borderline" and
no treatment is necessary.
Within the medical profession today there are those who state "It
is dangerous to give thyroxine when the thyroid biochemistry is within
normal concentrations because it will have serious effects on the
heart". Nobody is suggesting that thyroid medication is given
out willy nilly but if the patient is presenting with
signs and symptoms of hypothyroidism and T4 and or T3 concentrations
are at the lower end of normal then a cautious trial of thyroid replacement
therapy can do no harm, providing any heart conditions have been taken
into consideration.
DIAGNOSIS
CONFUSION - THYROID BLOOD TESTS
Studies
in 1,580 inpatients and in 630 patients admitted as medical emergencies
found that thyroid function tests performed as screening tests yielded
abnormal results in 33% and 20% of patients respectively. In both
studies, biochemical tests suggested thyroid disease incorrectly (that
is they gave false positive results) in 9 cases out of ten. Thus indiscriminate
use of thyroid function tests is more likely to confuse than to help.
REF: BMJ 2000; 320:1332-1334 (13thMay) Thyroid function tests-time
for a re-assessment. Page 9.
READ
SO MUCH MORE IN THE SECOND EDITION OF
'TEARS
BEHIND CLOSED DOORS'
We are all subjected to chemicals
IN THE FOOD WE EAT
IN THE AIR WE BREATHE
IN THE WATER WE DRINK.
AND THE MAJORITY OF
THESE CHEMICALS AFFECT THYROID FUNCTION BECAUSE THEY ARE ENDOCRINE
DISRUPTERS.
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